Born in 1963, Neyveli R. Santhanagopalan is a Carnatic music vocalist known for his traditional values in the rendition of classical compositions. Brought up in a musical environment at home, and initiated by his mother Jayalakshmi Ammal, he received rigorous training from Sangita Kalanidhi T.N. Seshagopalan. He is also proficient in the veena and percussion instruments. His contribution to Carnatic musicology has also been recognised.

The distinguishing features of his music style are his well-structured and cerebral approach to aspects of raga elaboration, focus on tonal quality, expertise in niraval and minimalist rendition of ragam-tanam-pallavi. In recent years he has struggled with vocal problems.